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KMID : 0914820050050020127
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Journal of the Korean Gastric Cancer Association
2005 Volume.5 No. 2 p.127 ~ p.132
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Hepatoid Adonocarcinoma of the Stomach with Liver Metastasis
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Kwon Woo-Il
Park Do-Joong
Lee Hyuk-Joon
Kim Woo-Ho
Yang Han-Kwang
Choi Kook-Jin
Lee Kuhn-Uk
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Abstract
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A hepatoid adenocarcinoma of stomach, a subtype of gastric cancr, is characterized by a histologic resemblance to a hepatocellular carcinoma and $\alpha$-feto protein production. Another feature is early metastasis to the liver and lymph nodes, thus revealing a poor prognosis. We report a case of a hepatoid adenocarcinoma of the stomach with liver metastasis. A 52-year-old male visited our hospital with a chief complaint of indigestion. Gastroscopic examination showed a Borrmann type-II lesion on the lesser curvature of the antrum. The CT scan showed a suspected advanced gastric cancer with liver metastasis. The serum AFP level was 123 ng/ml. A radical subtotal gastrectomy and a right hemihepatectomy were performed simultaneously. Pathologic examination confirmed the lesion to be confined to the submucosa. The gastric lesion was a hepatoid adenocarcinoma, and the hepatic lesion was a metastatic adenocarcinoma from the stomach. Therefore, he was classified as having stage IV (T1N1M1) gastric cancer. In cases of a hepatoid adenocarcinoma of the stomach, even patients with early gastric cancer can be staged into the poor prognostic group.
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KEYWORD
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Gastric cancer, Hepatoid adenocarcinoma, Liver metastasis
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